卡培他滨致严重糖尿病及低钾血症1例

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1临床资料患者女性,48岁。因“活动后气促、四肢乏力1月余,加重3 d”入院。患者1月余前无明显诱因下出现活动后气促,伴有四肢肢体乏力,3 d前觉乏力症状加重,步行约50 m、上2层楼梯即觉气促明显,伴有心悸。在外院门诊检查提示血钾为2.7 mmol·L-1,自行口服补钾治疗,但乏力症状无明显缓解,为进一步诊治收入院。近1月来患者发现双侧手指指间、双足足趾间皮肤皱褶处出现色素沉着,脸部颧骨区皮肤出现较多褐色色斑,无明显四肢麻木感。起病以来食欲明显 1 Clinical data Patient female, 48 years old. Because of “shortness of breath after activities, limb fatigue more than 1 month, increased 3 d ” admission. Patients with no obvious incentive before the event occurred after the first episode of shortness of breath, accompanied by limb weakness, 3 d before the onset of fatigue symptoms, walking about 50 m, on the 2-story staircase that is, to promote air conspicuous with palpitations. In outpatient outpatient examination prompted serum potassium 2.7 mmol·L-1, oral potassium treatment, but no significant alleviation of fatigue symptoms, for further diagnosis and treatment of income homes. Nearly a month patients found bilateral finger interphalangeal, double feet between the skin folds appear to pigmentation, facial cheekbones area more brown spots, no obvious limb numbness. Appetite since the onset of obvious
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