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目的:研究临界性高血压对左心室肥厚及左心室舒张功能的影响。方法:本文应用无创动态血压及二维彩色多普勒超声心动图检测方法对照研究92例临界高血压患者左心室重量指数(LVMI)及舒张功能与血压水平及血压节律的关系。结果:临界性高血压组左心室肥厚发生率18.5%,LVMI与对照组相比为107.2±13.5g比92.5±11.6g(P<0.01),LVMI与昼间收缩压及昼间收缩压负荷值相关性最显著(r分别为0.30及0.28,P<0.01),与24小时收缩压及收缩压夜间昼间比值亦有较好的相关性(r分别为0.25及0.22,P<0.05),临界性高血压组左心室舒张功能明显受损。结论:临界性高血压已不同程度的存在左心室结构及功能异常,收缩压水平及昼夜节律异常是左心室受累的主要因素。
Objective: To study the effects of critical hypertension on left ventricular hypertrophy and left ventricular diastolic function. Methods: In this study, noninvasive ambulatory blood pressure and two-dimensional color Doppler echocardiography detection of 92 patients with critical hypertensive patients with left ventricular mass index (LVMI) and diastolic function and blood pressure and blood pressure rhythm relationship. Results: The incidence of left ventricular hypertrophy in critical hypertensive group was 18.5%, LVMI was 107.2 ± 13.5g vs 92.5 ± 11.6g (P <0.01), LVMI and day Systolic blood pressure and daytime systolic blood pressure were the most significant (r = 0.30 and 0.28, respectively, P <0.01), and 24 hours systolic blood pressure and systolic blood pressure nighttime daytime ratio is also good Correlation (r = 0.25 and 0.22, respectively, P <0.05), left ventricular diastolic function was significantly impaired in the critical hypertensive group. Conclusion: There are different degrees of left ventricular structure and dysfunction in critical hypertension. Systolic blood pressure and circadian rhythm are the main factors of left ventricular involvement.