原发性肝癌的现代研究已有百余年历史。就治疗而言,50、60年代出现了第一次飞跃,即大肝癌可用肝叶切除的方法治疗,它使5～10%肝癌病人受益。第二次飞跃乃7O、80年代小肝癌的切除,它使另外5～10%病人受益。预期第三次飞跃可能是80年代出现的“大肝癌变小肝癌”的研究,它可能使第三个 The modern study of primary liver cancer has a history of more than 100 years. In terms of treatment, the first leap occurred in the 50s and 60s, that is, hepatocellular carcinoma can be treated by hepatectomy, and it benefits 5 to 10% of liver cancer patients. The second leap was the resection of small hepatocellular carcinoma in the 70s and 80s, which benefited another 5 to 10% of patients. It is expected that the third leap might be the study of “big hepatocellular carcinoma shrinking liver cancer” that appeared in the 1980s. It may make the third