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目的探索内蒙古乌海市成人超重肥胖和甜饮料(sugar-sweetened beverage,SSB)摄入与血尿酸(serum uric acid,SUA)的关系。方法采用多阶段分层整群抽样,对内蒙古乌海市5 995名居民展开横断面调查。采用多因素Logistic回归进行分析。结果男女超重、肥胖组SUA水平及高尿酸血症(hyperuricemia,HUA)检出率均高于正常组(均有P<0.05);男性SUA水平随SSB摄入量的增加依次增加(F=3.426,P=0.033,P_(trend)=0.010),SSB摄入频率较高者的SUA水平也较高(t=-2.204,P=0.028);女性SSB摄入量及摄入频率较高者,SUA水平反而较低(均有P<0.05)。多因素Logistic回归分析结果显示,男女超重、肥胖者HUA患病风险增加。超重肥胖与SSB摄入量对HUA检出率存在交互作用(均有P_(interaction)<0.05)。结论超重或肥胖是HUA的独立危险因素,摄入SSB会增加男性SUA水平。超重或肥胖同时增加SSB摄入会提高HUA患病风险。
Objective To explore the relationship between adult overweight and sugar-sweetened beverage (SSB) intake and serum uric acid (SUA) in Wuhai City, Inner Mongolia. Methods A multi-stage stratified cluster sampling was used to investigate the cross-sectional survey of 5 995 residents in Wuhai City, Inner Mongolia. Multivariate logistic regression analysis. Results The prevalence of SUA and hyperuricemia (HUA) in overweight and obesity group were higher than those in normal group (all P <0.05). The male SUA level increased with the increase of SSB intake (F = 3.426 (T = -2.204, P = 0.028). Female SSB intake and the higher frequency of ingestion were higher in women with higher SSB ingestion frequency (P = 0.033, P trend = 0.010) SUA levels were lower (all P <0.05). Multivariate Logistic regression analysis showed that the prevalence of HUA was increased in overweight and obese men and women. There was interaction between overweight and SSB intake on detection rate of HUA (both P <0.05). Conclusion Overweight or obesity is an independent risk factor for HUA. Inhaling SSB can increase SUA in men. Overweight or obesity while increasing SSB intake will increase the risk of HUA.