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目的分析超声引导下PTCD联合外科常规保守治疗和仅用外科常规保守治疗恶性梗阻性黄疸患者的临床治疗效果。方法随机选取该院2014年8月—2016年8月收治的58例恶性梗阻性黄疸患者的资料,将其分为对照组与观察组。其中对照组采用外科常规保守治疗,观察组采用PTCD联合外科常规保守治疗。观察两组患者治疗前后的临床症状、血清总胆红素(TB)、直接胆红素(DB)、碱性磷酸酶(ALP)、丙氨酸氨基转移酶(ALT)、白蛋白(Alb)的变化情况。结果观察组患者的血清总胆红素(98.2±27.8)滋mol/L、直接胆红素(79.8±22.7)滋mol/L,血清碱性磷酸酶(286.3±194.5)U/L、丙氨酸氨基转移酶(63.5±36.1)U/L,血清白蛋白(32.3±4.1)g/L,对照组患者血清总胆红素(141.1±98.7)滋mol/L、直接胆红素(126.3±97.9)滋mol/L,血清碱性磷酸酶(361.2±234.7)U/L、丙氨酸氨基转移酶(89.1±61.8)U/L,血清白蛋白(25.5±1.2)g/L,两组患者TB、DB、ALP、ALT、ALB差异有统计学意义(P﹤0.05)。结论超声引导下PTCD联合外科常规保守治疗恶性梗阻性黄疸患者效果比仅用外科常规保守治疗效果更好,患者肝功能恢复更明显能够有效降低患者的黄疸症状,值得医院推广和临床治疗。
OBJECTIVE: To analyze the clinical effect of ultrasound-guided PTCD in combination with conventional surgical conservative treatment and surgical conservative treatment of malignant obstructive jaundice. Methods A total of 58 patients with malignant obstructive jaundice admitted from August 2014 to August 2016 in our hospital were selected randomly and divided into control group and observation group. Among them, the control group was treated conservatively and the observation group was conservatively treated with PTCD combined with surgery. The clinical symptoms, serum total bilirubin (TB), direct bilirubin (DB), alkaline phosphatase (ALP), alanine aminotransferase (ALT) and albumin (Alb) Changes in the situation. Results The serum total bilirubin (98.2 ± 27.8) mol / L, direct bilirubin (79.8 ± 22.7) mol / L, serum alkaline phosphatase (286.3 ± 194.5) U / L, (63.5 ± 36.1) U / L, serum albumin (32.3 ± 4.1) g / L, serum total bilirubin (141.1 ± 98.7) mol / L and direct bilirubin 97.9 mol / L serum ALT 361.2 ± 234.7 U / L alanine aminotransferase 89.1 ± 61.8 U / L serum albumin 25.5 ± 1.2 g / L, two groups There were significant differences in TB, DB, ALP, ALT and ALB between the two groups (P <0.05). Conclusion Ultrasound-guided PTCD combined conservative surgical treatment of patients with malignant obstructive jaundice is more effective than the conventional surgical conservative treatment, and the recovery of liver function in patients with more obvious can effectively reduce the symptoms of jaundice in patients, it is worth the hospital to promote and clinical treatment.