论文部分内容阅读
本文介绍1989年～1993年在国内首次采用Spot点片法对辽宁地区正常儿童进行神经母细胞瘤(Neuroblastoma,NB)的早期筛查。在50350例正常儿童中,筛查出无临床症状的可疑病人4例。其spot点片法均为阳性,层析结果分别出现香草扁挑酸(VMA),高香草酸(HVA),香草乳酸(VLA);VMA定量超过正常值。经B超、磁共振(MRI)检查,3例均在左肾上腺发现肿物(3.5cm×2.0cm,2.0cm×2.0cm,2.0cm×2.5cm)诊断为NB.1例接受手术治疗。2例放射治疗,目前均健康生存。另1例经B超、磁共振多部位探查,未发现肿物,列为追踪观察对象。初得辽宁地区小儿NB发病率约为6/10万。
This article describes the first screening of neuroblastoma (NB) in normal children in Liaoning Province from 1989 to 1993 using Spot-point method. Among the 50350 normal children, 4 cases of suspicious patients without clinical symptoms were screened out. The spot spot method was positive, the chromatographic results were vanilla flat acid (VMA), vanillic acid (HVA), vanillic acid (VLA); VMA quantitative than normal. B ultrasound and magnetic resonance imaging (MRI) showed that all the 3 cases were diagnosed as having neoplasia of the left adrenal gland (3.5 cm × 2.0 cm, 2.0 cm × 2.0 cm, 2.0 cm × 2.5 cm). 2 cases of radiation therapy, are currently healthy living. Another case of B ultrasound, magnetic resonance multi-part exploration, found no tumor, as a follow-up observation object. The prevalence of pediatric NB in Liaoning Province was about 6 / 100,000.