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目的:探究腹腔镜下胃穿孔修补术对老年消化性溃疡穿孔的疗效。方法:对我院2009年11月-2011年9月收治的96例老年消化性溃疡患者,在征得患者及其家属同意的前提下按照随机数字表进行分组,观察组48例,采取腹腔镜下胃穿孔修补术进行治疗,对照组48例,采取传统开腹手术治疗,对比两组患者的手术情况、疼痛评分及复发情况,探讨腹腔镜下胃穿孔修补术的疗效。结果:观察组手术时间(89.3±11.7)m i n,肛门排气时间(2.6±0.4)d,住院时间(9.2±3.0)d,无死亡患者;对照组手术时间(92.6±12.9)min,肛门排气时间(3.2±1.1)d,住院时间(12.4±4.6)d,死亡2例,死亡率4.2%。观察组肛门排气时间、住院时间及死亡率均显著低于对照组(p<0.05),两组患者手术时间无明显统计学差异(p>0.05)。观察组患者术后1d疼痛评分(3.3±0.7)分,术后3d疼痛评分(2.2±0.4)分,术后7d疼痛评分(1.3±0.3)分,6例使用镇痛剂,镇痛剂使用率12.5%;对照组患者术后1 d疼痛评分(5.3±1.0)分,术后3d疼痛评分(3.2±0.6)分,术后7d疼痛评分(1.9±0.4)分,22例使用镇痛剂,镇痛剂使用率45.8%。观察组患者术后1d、3d、7d疼痛评分及镇痛剂使用率均显著低于对照组,两组数据对比存在统计学差异(p<0.05)。两组所有患者均获得有效随访,观察组无复发,对照组3例复发,复发率6.25%,观察组复发率明显低于对照组。结论:腹腔镜下胃穿孔修补术创伤小、手术过程短、术后恢复快,且疼痛程度明显低于传统开腹手术,对于高龄患者而言是一类极佳的手术治疗方式,具有良好的治疗效果,能够有效保证患者术后生活质量,值得临床广泛推广。“,”Objective To explore the curative effect of laparoscopic repair of perforated gastric perforation of peptic ulcer in the elderly. Methods 96 cases of elderly patients with peptic ulcer in our hospital in 2009 November-2011 year in September, were grouped according to the random number table based on the consent of the patients and their families consent, the observation group 48 cases, taking laparoscopic gastric perforation repair were treated, 48 cases in the control group, the traditional open operation treatment, operation situation, pain score and recurrence were compared between two groups, to explore the effect of laparoscopic repair of gastric perforation. Results The operation time of the observation group ( 89.3± 11.7 ) min, anal exhaust time ( 2.6 ±0.4 ) d, the hospitalization time (9.2 ±3 ) d, and no death of patients with operation time;control group ( 92.6± 12.9 ) min, anal exhaust time ( 3.2 ±1.1 ) d, the hospitalization time (12.4 ±4.6 ) d, died in 2 cases, the mortality rate was 4.2%. The observation group anal exhaust time, hospitalization time and mortality were significantly lower than those in control group ( P0.05 ). Patients in the observation group after 1 D pain score ( 3.3 ±0.7 )%, 3 postoperative D pain score ( 2.2 ±0.4 )%, 7 postoperative D pain score ( 1.3 ±0.3 ), 6 cases of analgesic use, 12.5%utilization rate and analgesic agent;the control group of patients after 1 pain score ( D 5.3 ±1 )%, 3 postoperative D pain score ( 3.2 ±0.6 )%, 7 postoperative D pain score ( 1.9 ±0.4 ), 22 cases of analgesic use, 45.8%utilization rate of analgesic. Patients in the observation group after 1 D, 3 D, 7 d pain scores and analgesic use rate were significantly lower than the control group, there was significant difference between two groups of data (P<0.05 ). All patients were followed up for two groups, the observation group had no recurrence, 3 cases in the control group relapsed, the relapse rate was 6.25%, the recurrence rate of the observation group was significantly lower than the control group. Conclusion Laparoscopic gastric perforation repair small trauma, operation process is short, quick recovery after operation, and the pain was significantly less than traditional open operation for elderly patients, treatment is a kind of excellent operation, has good treatment effect, can effectively guarantee the quality of life of patients, is worthy of clinical application.