论文部分内容阅读
目的研究输卵管切除术对卵巢功能的影响。方法选取2008年10月至2010年10月来新野县人民医院行体外受精-胚胎移植的双侧输卵管切除不孕患者56例作为研究组;选取同期双侧输卵管堵塞但未采取切除治疗的不孕患者56例作为对照组。两组患者均进行基础内分泌测定、体外受精-胚胎移植治疗。观察输卵管切除术对患者的基础内分泌、促性腺激素用量以及超促排卵周期中获卵情况的影响。结果研究组患者的基础内分泌指标与对照组比较差异未见统计学意义(P>0.05)。研究组手术时间低于2年的患者和手术时间高于5年的患者基础内分泌指标比较差异未见统计学意义(P>0.05)。研究组患者临床促性腺激素用量和用药天数较对照组多,差异有统计学意义(P<0.05),而获卵数少于对照组,两组比较差异有统计学意义(P<0.05)。结论行双侧输卵管切除术进行治疗的患者在短时期内基础内分泌无明显的改变,但双侧卵巢反应性有明显变化。临床建议,行输卵管妊娠手术的患者如果想保留生育功能,则最好保留输卵管,但病情进展要求输卵管切除的患者则应最大程度地降低对输卵管系膜损伤。
Objective To study the effect of tubal excision on ovarian function. Methods From October 2008 to October 2010 to Xinye County People’s Hospital in vitro fertilization and embryo transfer bilateral tubal infertility patients 56 cases as the study group; select the same period of bilateral tubal occlusion but did not take the treatment of infertility 56 patients as a control group. Two groups of patients were based on endocrine tests, in vitro fertilization - embryo transfer treatment. To observe the effect of tubal resection on patients’ basal endocrine, gonadotrophin dosage and ovulation during superovulation cycle. Results There was no significant difference in basal endocrine index between study group and control group (P> 0.05). There was no significant difference in basal endocrine index between study group less than 2 years and patients with operation time above 5 years (P> 0.05). The study group had more gonadotropin and medication days than the control group (P <0.05), while the number of oocytes retrieved was less than that of the control group. The difference between the two groups was statistically significant (P <0.05). Conclusions Patients undergoing bilateral salpingo-oophorectomy have no significant changes in basal endocrine within a short period of time, but have significant changes in bilateral ovarian reactivity. Clinical recommendations, tubal pregnancy surgery patients who want to retain reproductive function, it is best to retain the fallopian tube, but the condition requires tubal resection patients should minimize the damage to the tubal mesangial.