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本实验研制出高(1400～1600μg碘/个),中(600～800μg碘/个)、低(300～400μg碘/个)三种不同含碘量的鸡蛋。 给大鼠每公斤体重3.38mg碘的碘蛋粉,喂10天后,动物无一死亡,摄食量和对照组无差别,体重略高于对照组。人体每日服一个高剂量碘蛋三个月后,测血清T_3和T_4浓度,实验前后无明显变化,均在正常范围。临床观察97名(糖尿病38例,高胆固醇血症49例,高血压10例)患者长达63～90天,均末发现不良副作用。 38例糖尿病人每日服1个高剂量碘蛋,治疗三个疗程(每个疗程21天)后的结果是:第一疗程血糖下降40.9mg％(P<0.01),第二疗程32.5mg％(P<0.01),第三疗程48.9mg％(P<0.01)。尿糖下降也非常显著。49例高胆固醇血症患者经过三个月的治疗后,血清总胆固醇第一个月下降19.0mg％(P<0.05),第二个月14.0mg％(P<0.05),第三个月21.0mg％(P<0.05)。同时观察10例高血压患者,共二个月,收缩压第一个月下降15.3mmHg(P<0.05),第二个月15.9 mmHg(P<0.05)。舒张压第一个月下降8.7mmHg(P<0.05),第二个月略有回升。
The experiment developed high (1400 ~ 1600μg iodine / one), medium (600 ~ 800μg iodine / one), low (300 ~ 400μg iodine / one) three different iodine content of eggs. To rats per kilogram of body weight 3.38mg Iodine iodine powder, feed 10 days after the animals without a death, the food intake and the control group no difference, slightly higher body weight than the control group. Serum human daily dose of a high dose of iodine three months later, serum T_3 and T_4 concentrations, no significant changes before and after the experiment, are in the normal range. Clinical observation of 97 patients (38 cases of diabetes, hypercholesterolemia in 49 cases, hypertension in 10 patients) up to 63 to 90 days, were found at the end of adverse side effects. 38 cases of diabetic patients taking 1 high dose of iodine daily, the results of treatment of three courses (21 days each course): the first course of treatment decreased blood glucose by 40.9mg% (P <0.01), the second course of 32.5mg% (P <0.01), and the third course was 48.9mg% (P <0.01). Declining urine is also very significant. In the 49 patients with hypercholesterolemia, the serum total cholesterol decreased by 19.0 mg% (P <0.05) in the first month, 14.0 mg% in the second month (P <0.05) and 21.0 mg% (P <0.05). At the same time, 10 patients with hypertension were observed for two months. Systolic blood pressure decreased 15.3 mmHg in the first month (P <0.05) and 15.9 mmHg in the second month (P <0.05). Diastolic blood pressure decreased by 8.7mmHg in the first month (P <0.05), and slightly increased in the second month.