[目的]探讨枳实消痞丸联合枸橼酸西沙必利治疗慢传输型便秘的作用。[方法]将138例患者随机分为2组,均予枸橼酸西沙比利治疗基础上,对照组加服四磨汤口服液,治疗组加服枳实消痞丸。对2组患者治疗2周、4周及治疗结束后2周的治愈率、总有效率、无效率,治疗前后便秘主要症状积分进行比较。[结果]治疗组治疗2周、4周及治疗结束后2周的总有效率分别为91.66%、95.83%及86.11%,对照组分别为81.58%、81.58%及65.79%;2组比较差异有统计学意义(P<0.01);2组治疗前、后便秘主要症状积分比较差异均有统计学意义(P<0.05),2组间治疗后积分比较差异有统计学意义(P<0.01)。[结论]枳实消痞丸联合枸橼酸西沙必利治疗慢传输型便秘效果好,复发率低,优势明显。 [Objective] To investigate the effect of Zhishi Xiaopi Pills combined with cisapride citrate on slow transit constipation. [Method] 138 patients were randomly divided into two groups, all based on cisapride citrate treatment, the control group plus serving Si Mogang oral liquid, the treatment group plus Zhishi Xiaopi pill. The cure rate, total effective rate, ineffective rate and the main symptom scores of constipation before and after treatment were compared between two groups in two weeks, four weeks and two weeks after the end of treatment. [Results] The total effective rates in the treatment group at 2 weeks, 4 weeks and 2 weeks after the treatment were 91.66%, 95.83% and 86.11%, respectively, while those in the control group were 81.58%, 81.58% and 65.79%, respectively (P <0.01). There were significant differences in the main symptom scores of constipation between the two groups before and after treatment (P <0.05), and there was significant difference between the two groups after treatment (P <0.01). [Conclusion] Zhishi Xiaopi Pill combined with cisapride citrate has good effect on slow transit constipation with low recurrence rate and obvious advantages.