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目的探讨血清尿酸(uric acid,UA)、C反应蛋白(Creactive protein,CRP)水平与急性脑梗死(acute cerebral infarction,ACI)的病情严重程度及转归的相关性。方法 ACI组按神经功能缺损程度分为轻型、中型及重型三组。ACI组及对照组均进行UA、CRP水平的检测。将ACI组与对照组、ACI三组间的UA、CRP水平及UA、CRP正常组与高UA、CRP组的转归情况进行统计学分析。结果 ACI组UA、CRP水平较对照组明显增高;轻型、中型及重型三组间差异均具有统计学意义,P<0.05。UA、CRP正常组与高UA、CRP组的预后比较,经治疗明显进步、无变化及死亡差异均具有统计学意义,P<0.05。结论 UA、CRP可作为急性梗死病情严重程度及其发展及预后判断的指标之一,可作为对ACI干预的实验依据。
Objective To investigate the relationship between serum uric acid (UA), Creactive protein (CRP) levels and severity of acute cerebral infarction (ACI) and prognosis. Methods ACI group according to the degree of neurological deficit into light, medium and heavy three groups. ACI group and control group were detected UA, CRP levels. The levels of UA and CRP in the ACI group and the control group and the ACI group and the prognosis of the UA and CRP normal group and the high UA and CRP group were statistically analyzed. Results The levels of UA and CRP in ACI group were significantly higher than those in control group. The differences among the three groups were statistically significant (P <0.05). The prognosis of UA, CRP normal group and high UA and CRP group were significantly improved after treatment, no difference in change and death were statistically significant, P <0.05. Conclusion UA and CRP can be used as indicators of the severity of acute infarction, its development and prognosis, which can be used as the experimental basis for the intervention of ACI.