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自主功能亢进性甲状腺腺瘤是Ｐｌｕｍｍｅｒｓ甲亢的主要病因，其特点是腺瘤不受下丘脑、垂体的调节，表现为功能自主，当临床表现机能亢进时，称为甲状腺毒性腺瘤［１］。对其研究的重点是：①甲状腺非毒性腺瘤发展成毒性腺瘤的速度及频度；②是否存在Ｔ３型Ｐｌｕｍｍｅｒ
Autonomous hyperthyroidism thyroid adenoma is the main cause of Plum mers hyperthyroidism. It is characterized by adenomas not regulating the hypothalamus and pituitary, showing functional autonomy. When the clinical manifestations hyperactivity, it is called thyrotoxic adenoma [1 ]. The focus of their research is: 1 the rate and frequency of nontoxic adenomas developing into toxic adenomas; 2 whether there is a T3 Plummer