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目的探讨代谢综合征(MS)与颈动脉内中膜厚度(IMT)的相关性。方法选择健康查体的成人7180例,根据MS的诊断标准分为MS组(1457例)和非MS组(5723例),测量所有入选者身高、体重计算体质量指数(BMI),测量收缩压(SBP)、舒张压(DBP),检测空腹血糖(FPG)、总胆固醇(TC)、低密度脂蛋白胆固醇(DH-C)、高密度脂蛋白胆固醇(HDL-C)、三酰甘油(TG);经颈动脉超声检测IMT;比较MS与非MS组入选者IMT及相关指标。结果 MS组入选者IMT明显高于非MS组入选者IMT(P<0.01),校正年龄、性别等因素后,MS组入选者IMT明显高于非MS组入选者IMT,差异仍有统计学意义(P<0.05)。结论成人汉族人群MS可以增加动粥样硬化发生的风险,对MS患者及早进行颈动脉超声检查,将有肋于心血管事件的一级预防。
Objective To investigate the correlation between metabolic syndrome (MS) and carotid intima-media thickness (IMT). Methods Seventy-one thousand healthy adults were enrolled in this study. According to the diagnostic criteria of MS, MS patients (1457 cases) and non-MS patients (5723 cases) were enrolled in this study. Height and weight were calculated for body mass index (BMI) SBP, DBP, FPG, TC, DH-C, HDL-C and triglyceride (TG) ); IMT was detected by carotid ultrasonography; IMT and related indicators of MS and non-MS group were compared. Results The IMT of MS group was significantly higher than that of non-MS group (P <0.01). After adjusting for age and gender, the IMT of MS group was significantly higher than that of non-MS group, the difference was still statistically significant (P <0.05). Conclusions MS can increase the risk of atherosclerosis in adult Han population. Carotid ultrasonography can be performed early in MS patients, and there is a primary prevention of ribbed cardiovascular events.