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目的了解云南省肾综合征出血热流行病学特点,提供科学的防治依据。方法收集全省2006年疫情资料,并在监测点采集人血清及鼠肺和鼠血清作汉坦病毒抗原和抗体检查。结果2006年全省共报告本病39例,死亡1例,年发病率为0.05/10万,病死率为2.56%。主要发病地区为大理州、昆明市和红河州。疫区人群隐性感染率为6.90%。2006年在泸西、寻甸和永胜监测点捕获鼠类10种810只,居民区以褐家鼠和黄胸鼠为优势鼠种,野外以高山姬鼠、中华姬鼠和大绒鼠为优势鼠种。鼠间汉坦病毒带毒率为4.13%,带病毒鼠种为褐家鼠、黄胸鼠、高山姬鼠、中华姬鼠和大绒鼠。结论监测区内存在以褐家鼠和黄胸鼠为主要宿主的家鼠型疫源地,也存在着以高山姬鼠、中华姬鼠和大绒鼠为主的野鼠型疫源地。应采取以灭鼠和接种家鼠型或两型混合疫苗为主的防治措施。
Objective To understand the epidemiological characteristics of hemorrhagic fever with renal syndrome in Yunnan Province and provide scientific basis for prevention and treatment. Methods The data of epidemic situation in the province in 2006 were collected, and human serum, mouse lung and mouse serum were collected for the detection of Hantavirus antigen and antibody at the monitoring sites. Results In 2006, a total of 39 cases of this disease were reported in the province and 1 died. The annual incidence rate was 0.05 / 100,000 and the case fatality rate was 2.56%. The main incidence of Dali Prefecture, Kunming and Honghe Prefecture. Infectious area crowd latent infection rate was 6.90%. In 2006, 10 810 species of rodents were captured in Luxi, Xundian and Yongsheng monitoring sites. Rattus norvegicus and Rattus flavipectus were the dominant species in the residential area. In the field, alpine Apodemus, Dominant species of rats. Hantaan virus poisoning rate was 4.13%, with the virus rat species Rattus norvegicus, Rattus flavipectus, alpine Apodemus, Apodemus and mammoth. Conclusion There are foci of domestic mice with Rattus norvegicus and Rattus flavipectus as host hosts in the monitoring area. There are also wild-type foci in Alzheimer’s disease, Apodemus agrarius and Plutella xylostella. Should be taken to rodent and vaccinated mice or two types of mixed vaccine-based control measures.