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间质细胞肿瘤的组织学和超微结构特征以及免疫组化表现为CD117阳性确立了GIST的诊断。手术是GIST的主要治疗方法,甲磺酸伊马替尼为代表的靶向治疗,给GIST的治疗带来突破性进展。现回顾总结近几年国内外关于胃肠间质瘤(GIST)在诊断和治疗方面的研究进展。
Histological and ultrastructural features of stromal tumors as well as immunohistochemical findings of CD117 established the diagnosis of GIST. Surgery is the main treatment of GIST, imatinib mesylate is the representative of the targeted treatment, to bring a breakthrough in the treatment of GIST. Now review the recent years at home and abroad on gastrointestinal stromal tumors (GIST) in the diagnosis and treatment of research progress.