自从伍勒在1828年合成尿素、使有机化学成为一门独立的学科以后,有机合成贯穿了整个的有机化学发展史。可以设想,如果没有已知的三千多个有机反应作为后盾,特别是如果没有那么二百多个在有机合成中有普遍应用价值的有机反应的发展和推广使用,有机化学、生物化学、药物化学、高分子化学以及有关的工业如染料工业、制药工业、合成橡胶和塑料工业等等,要发展到目前这样的水平是完全不可能的。因此有机合成的重要性是不言而喻的。另一方面,现代有机合成化学已经成为一门与物理有机化学和生物有机化学相互交织、相互 Since the synthesis of urea in 1828, Woolech made organic chemistry an independent discipline, organic synthesis throughout the history of the development of organic chemistry. It is conceivable that if no more than 3,000 known organic reactions are supported, especially if there are not more than two hundred organic reactions of general application value in organic synthesis developed and promoted, organic chemistry, biochemistry, drugs Chemistry, polymer chemistry and related industries such as the dye industry, the pharmaceutical industry, the synthetic rubber and plastics industries, etc., are not possible to develop to the current level. Therefore, the importance of organic synthesis is self-evident. On the other hand, modern organic synthesis chemistry has become a physical and organic chemistry and biological organic chemistry intertwined with each other