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巨细胞病毒(CMV)是通过胎盘感染胎儿的主要病毒,也是3个月以下婴儿肝炎的主要病原之一。我科1983～1984年收治10例经血清学证实的婴儿巨细胞病毒肝炎,经随访4例得到结果,现介绍如下。临床资料:4例均系第1胎、人工喂养女婴,分娩情况良好,出生体重2.7～3.8kg。其中3例在患病后输过1～2次全血或血浆。主要临床表现及实验室检查见附表。血清学检查抗-HAV-IgM、抗-HBe-lgM、抗EBV-IgM4例均为阴性,抗-CMV-IgM[IF]及抗-CMV-IgG[ELISA]4例均为阳性。出院时病情均好转,2例黄疸消退,2例黄疸减轻。
Cytomegalovirus (CMV) is the major virus that infects the fetus through the placenta and is also one of the major pathogens of infant hepatitis under 3 months. Our department from 1983 to 1984 admitted 10 cases of serological confirmed infant cytomegalovirus hepatitis, were followed up in 4 cases, the results are as follows. Clinical data: 4 cases were the first child, artificial feeding of girls, childbirth is good, birth weight 2.7 ~ 3.8kg. Three of them lost 1 or 2 whole blood or plasma after their illness. The main clinical manifestations and laboratory tests see schedule. Anti-HAV-IgM, anti-HBe-IgM and anti-EBV-IgM were negative in 4 cases and positive in 4 cases of anti-CMV-IgM [IF] and anti-CMV-IgG [ELISA]. Condition was improved at discharge, 2 cases of jaundice subsided, 2 cases of jaundice reduced.