论文部分内容阅读
[目的]观察化痰祛瘀通络方联合西药治疗风痰入络型急性脑梗塞疗效。[方法]使用随机平行对照方法,将103例住院及门诊患者按就诊顺序随机分为两组,对照组51例西医常规治疗,治疗组52例化痰祛瘀通络方(生黄芪30g,半夏20g,丹参、当归各15g,生地黄20g,川芎、赤芍、三七各15g,水蛭、石菖蒲、葛根、川牛膝、酒大黄各10g)1剂/d,水煎2次,取混合液汁400mL分早晚口服,口服困难者予鼻饲给药。言语不清加远志10g以祛痰宣窍,痰瘀交阻加桃仁10g以活血化瘀;风阳上扰加天麻10g以平肝潜阳。西药治疗同对照组。连续治疗15d为1疗程。观测临床症状、血液流变学指标。连续治疗3疗程,判定疗效。[结果]治疗组痊愈11例,显效15例,有效20例,无效6例,总有效率88.46%;对照组痊愈8例,显效13例,有效15例,无效16例,总有效率70.59%,治疗组疗效优于对照组(P<0.05);血液流变学指标均有改善(P<0.05,P<0.01),治疗组改善优于对照组(P<0.01)。[结论]化痰祛瘀通络方联合西药治疗风痰入络型急性脑梗塞疗效确切,改善血液流变学指标,缓解脑细胞缺氧、缺血和脑循环障碍。
[Objective] To observe the curative effect of Huatan Quyu Tongluo Recipe combined with western medicine in treating phlegm-phlegm-perfused acute cerebral infarction. [Methods] Using randomized parallel control method, 103 inpatients and outpatients were randomly divided into two groups according to the order of treatment. In the control group, 51 cases were treated routinely with Western medicine. The treatment group received 52 cases of Phlegm Quyu Tongluo Recipe (raw Astragalus 30g, half Radix Angelicae Sinensis 20g, Radix Angelicae Sinensis 15g, Radix Rehmanniae Preparata 20g, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Panax Notoginseng 15g, Leech, Shichangpu, Pueraria, Radix Achyranthis, Rhubarb 10g respectively. Mixing juice 400mL morning and evening oral administration, oral administration to nasal administration. Unacceptable add Polygala 10g to expectorant orgiastica, phlegm and blood obstruction plus peach 10g to promote blood circulation; wind on the disturbance of Gastrodia 10g Pinggan Qian Yang. Western medicine treatment with the control group. Continuous treatment 15d for a course of treatment. Observation of clinical symptoms, hemorheology indicators. Continuous treatment of 3 courses to determine the efficacy. [Results] The treatment group cured in 11 cases, markedly effective in 15 cases, effective in 20 cases, ineffective in 6 cases, the total effective rate was 88.46%; control group cured in 8 cases, markedly effective in 13 cases, effective in 15 cases, ineffective in 16 cases, the total effective rate was 70.59% (P <0.05). The indexes of hemorheology were all improved (P <0.05, P <0.01), and those of the treatment group were better than those of the control group (P <0.01). [Conclusion] Huatan Quyu Tongluo Recipe combined with western medicine is effective in treating acute cerebral infarction with wind phlegm phlegm. It can improve the indexes of hemorheology and alleviate the hypoxia, ischemia and cerebral circulation disorders of brain cells.