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目的观察克拉霉素干糖浆治疗旅行中小儿肺炎支原体肺炎的效果。方法应用克拉霉素干糖浆对1～14岁的旅行中儿童肺炎支原体肺炎46例的治疗效果与同期对照组2～14岁旅行中儿童64例应用红霉素治疗作比较。结果应用克拉霉素干糖浆治疗效果优于红霉素组,X~2=6.01,P<0.05,差异有显著意义;且胃肠道反应发生率明显低于红霉素组,X~2=20.88,P<0.001,差异有非常显著性。结论克拉霉素干糖浆治疗旅行中小儿肺炎支原体肺炎疗效优于红霉素,且胃肠道反应明显比红霉素小。
Objective To observe the effect of clarithromycin in the treatment of children with Mycoplasma pneumoniae pneumonia. Methods The clinical efficacy of clarithromycin in syrup was evaluated in 46 children aged 1-14 years with travel of children with Mycoplasma pneumoniae pneumonia and 64 cases of children with travel 2 to 14 years old in the same control group were treated with erythromycin. Results The application of clarithromycin in the treatment of dry syrup was better than that of the erythromycin group, X ~ 2 = 6.01, P <0.05, the difference was significant; and the incidence of gastrointestinal reaction was significantly lower than the erythromycin group, X ~ 2 = 20.88, P <0.001, the difference is very significant. Conclusion Clarithromycin dry syrup in the treatment of children with Mycoplasma pneumoniae pneumonia is superior to erythromycin, and the gastrointestinal reaction was significantly less than that of erythromycin.