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本文对６６例原发肾病综合征患者进行病理类型与临床疗效分析。最常见病理类型为系膜增殖性肾炎，占４２．５％，其次为膜性肾病，占３２．５％，ＩｇＡ肾病占１５．０％。微小病变型及系膜增殖性肾炎对激素及免疫抑制剂治疗效果好，膜性肾病治疗效果差。不同病理类型患者病理损害程度与疗效相关。伴肾小管间质病变者治疗效果差（Ｐ＜０．０５）。ＮＳⅠ型疗效明显优于ＮＳⅡ型（Ｐ＜０．０５）。５０岁以下原发肾病综合征（ＰＮＳ）疗效明显优于５０岁以上者（Ｐ＜０．０１）。
66 cases of primary nephrotic syndrome in patients with pathological type and clinical efficacy analysis. The most common pathological type of mesangial proliferative glomerulonephritis, accounting for 42.5%, followed by membranous nephropathy, accounting for 32.5%, IgA nephropathy accounted for 15.0%. Small lesions and mesangial proliferative glomerulonephritis and immunosuppressive agents have good therapeutic effect, and membranous nephropathy has poor therapeutic effect. Different pathological types of pathological lesions and the degree of efficacy. Treatment of patients with tubulointerstitial lesions were poor (P <0.05). NS Ⅰ type efficacy was significantly better than NS Ⅱ type (P <0.05). Primary nephrotic syndrome (PNS) under 50 years of age was significantly better than those over 50 years of age (P <0.01).