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从1500例肌肉活检标本中经过组织化学研究发现35例有特发性炎性肌病的病理诊断。其中6例为包含体肌炎。此6例的肌肉活检标本经过低温切片,半薄(Semithin)Epon切片的相差显微镜检和电子显微镜检查。文章从病理上,临床上描述了包含体肌炎同其他特发性炎性肌病的不同之处。在低温切片上,包含体肌炎的肌肉活检的显著特征是空泡中含有嗜硷颗粒,炎性浸润,坏死、再生,核异常,肌纤维萎缩,胶原纤维增生和毛细血管异常丰富,其中最特异的并且固定的特征是肌肉纤维中空泡形成,并含有小的嗜硷颗粒。以上发现能由半薄Epon切片的相差显微镜检证实。
From 1500 muscle biopsy specimens after histochemical study found 35 cases of idiopathic inflammatory myopathy pathological diagnosis. Six of them included body myositis. Six of these muscle biopsy specimens were examined by phase contrast microscopy and electron microscopy of cryosections and Semithin Epon sections. The article pathologically, clinically described the body contains the myositis and other idiopathic inflammatory myopathy different. A prominent feature of muscle biopsies containing body myositis at cryosections is the presence of vacuolar opacity particles, inflammatory infiltration, necrosis, regeneration, nuclear abnormalities, muscle fiber atrophy, hyperplasia of collagen fibers, and abnormal capillary vessels, the most specific of which The fixed and fixed feature is the formation of vacuoles in muscle fibers and contains small particles of alkaloids. The above findings can be confirmed by phase contrast microscopy of a semi-thin Epon section.