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目的:研究胺碘酮治疗心律失常对QT间期及QT间期离散度(QTd)的影响。方法:随机选取心律失常患者50例,予以胺碘酮治疗6周,比较治疗前后心律失常的疗效及QT间期与QTd的变化。结果:治疗后心律失常均明显减少,有效率85.2%,QTd明显缩短,由(61.03±9.20)ms减至(32.8±14.1)ms(P<0.01)。结论:胺碘酮能有效减少恶性心律失常发生,而且使患者QTd明显缩小。
Objective: To investigate the effect of amiodarone on QT interval and QT interval dispersion (QTd). Methods: Randomly selected 50 patients with arrhythmia, amiodarone treatment for 6 weeks, compared the efficacy of arrhythmia before and after treatment and QT interval and QTd changes. Results: After treatment, the arrhythmia was significantly reduced with an effective rate of 85.2%. QTd was significantly shortened from 61.03 ± 9.20 ms to 32.8 ± 14.1 ms (P <0.01). Conclusion: Amiodarone can effectively reduce the incidence of malignant arrhythmia, and make patients QTd significantly reduced.