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目的:探讨联合应用稳心颗粒和酒石酸美托洛尔治疗室性心律失常的临床疗效和安全性,旨在为室性心律失常的规范治疗提供参考依据。方法:将我院心内科2011年1月~2011年12月收治的100例室性心律失常患者视为研究对象并应用随机数字表法将此100例患者分为两组,即对照组和实验组。对照组患者单纯应用酒石酸美托洛尔片进行治疗,实验组患者在对照组患者治疗的基础上加用稳心颗粒进行治疗。治疗2周后,对比两组患者的治疗效果、心电图改善情况和不良反应发生情况。结果:实验组患者治疗的总有效率(96.00%)高于对照组患者(74.00%),且两组间的差异具有显著性(P<0.05);实验组患者的心电图改善率(94.00%)高于对照组患者(80.00%),且两组间的差异具有显著性(P<0.05);在不良反应发生方面,两组间的差异无显著性(P>0.05),不具有统计学意义。结论:联合应用稳心颗粒和酒石酸美托洛尔片治疗室性心律失常具有疗效显著、安全性高、不良反应少等优点,是一种值得在临床上进一步推广和应用的室性心律失常治疗法。
Objective: To explore the clinical efficacy and safety of combining Wenxin Granules and metoprolol tartrate in the treatment of ventricular arrhythmia, aiming to provide a reference for the standard treatment of ventricular arrhythmia. Methods: A total of 100 patients with ventricular arrhythmia admitted from January 2011 to December 2011 in our hospital were regarded as the research subjects. The 100 patients were divided into two groups according to the random number table (control group and experiment group. Patients in the control group were treated with Metoprolol tartrate tablets only. Patients in the experimental group were treated with Wenxin granules on the basis of the treatment of patients in the control group. After 2 weeks of treatment, the two groups of patients were compared, the treatment effect, ECG improvement and adverse reactions. Results: The total effective rate (96.00%) in the experimental group was significantly higher than that in the control group (74.00%), and the difference between the two groups was significant (P <0.05). The improvement rate of electrocardiogram (94.00% (P <0.05). There was no significant difference between the two groups in the incidence of adverse reactions (P> 0.05), which was not statistically significant . Conclusion: The combination of Wenshen granules and metoprolol tartrate tablets in the treatment of ventricular arrhythmia has the advantages of significant curative effect, high safety and less adverse reactions. It is a ventricular arrhythmia treatment worthy of further popularization and application in clinic law.