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患者,女,60岁。患者6年前受凉后出现面色苍白,四肢乏力,伴发热,最高达38.5℃,咳嗽,有白色黏痰,全身皮肤发黄。当地医院检查血常规:WBC 5.1×10~9/L,Hb 67g/L,BPC 210×10~9/L,网织红细胞占0.200,网织红细胞绝对值620×10~9/L;骨髓象提示为增生性贫血;直接抗人球蛋白试验(DAT)阳性:IgG、C_3混合型;阵发性睡眠性血红蛋白尿症(PNH)相关检查显示红细胞和白细胞表面 CD55和 CD59抗原均正常表达。诊断为温抗体型自身免疫性溶血性贫血(AIHA)。给予泼尼松50 mg/d 及对症治疗后,症状好转并
Patient, female, 60 years old. Patient 6 years ago after the cold appeared pale, limb weakness, fever, up to 38.5 ℃, cough, white phlegm, yellow skin system. Local hospital blood tests: WBC 5.1 × 10 ~ 9 / L, Hb 67g / L, BPC 210 × 10 ~ 9 / L, reticulocytes accounted for 0.200, reticulocytes absolute 620 × 10 ~ 9 / L; Prompt for the proliferation of anemia; direct anti-human globulin test (DAT) positive: IgG, C_3 mixed type; paroxysmal nocturnal hemoglobinuria (PNH) related examination showed that CD55 and CD59 antigens on the red blood cells and white blood cells were normal expression. Diagnosed with warm-type autoimmune hemolytic anemia (AIHA). After given prednisone 50 mg / d and symptomatic treatment, the symptoms improved