Objective: The aim of the study was to investigate the efficacy of digital radiography(DR), computed tomography(CT) and magnetic resonance imaging(MRI) in bone tumors. Methods: Fifty-five patients with histologically confirmed bone tumors underwent imaging examinations. Fifty-five patients were performed DR, 21 CT and 20 MRI. Results: DR of 51 patients clearly revealed bone changes. DR of 40 patients well showed marginal. Twenty tumors appeared periosteal reaction on DR and 19 calcification on DR. CT scan of 21 patients clearly depicted bone changes, marginal and calcification and CT scan of 8 revealed periosteal reaction. MRI scan of 20 patients all showed marginal and soft-tissue mass and bone marrow edema was prominent in 8 patients. Conclusion: DR is the first imaging approach for born tumors. CT well reveal the extent and minute structure of the bone tumors, the extent, soft-tissue mass and bone marrow edema are more dramatically demonstrated on MRI imaging. DR integrates with CT and MRI, is helpful in diagnosis of bone tumors. Objective: The aim of the study was to investigate the efficacy of digital radiography (DR), computed tomography (CT) and magnetic resonance imaging (MRI) in bone tumors. Methods: Fifty-five patients with histologically confirmed bone tumors underwent imaging examinations. Fifty-five patients were performed DR, 21 CT and 20 MRI. Results: DR of 51 patients clearly revealed bone changes. Twenty tumors had periosteal reaction on DR and 19 calcification on DR. CT scan of 21 patients clearly depicted bone changes, marginal and calcification and CT scan of 8 revealed periosteal reaction. MRI scan of 20 patients all showed marginal and soft-tissue mass and bone marrow edema was prominent in 8 patients. Conclusion: DR is the first imaging approach for born tumors. CT well reveal the extent and minute structure of the bone tumors, the extent, soft-tissue mass and bone marrow edema are more likely demonstrated on MRI imaging. and MRI, is helpful in diagnosis of bone tumors.