目的：观察强脉冲光联合长脉冲l 064nmNd：YAG激光治疗面部毛细血管扩张症的临床疗效及安全性。方法：将86例面部毛细血管扩张症患者随机分为A、B两组，每组各43例，其中A组单纯采用强脉冲光治疗，B组采用强脉冲光联合长脉冲1064nmNd：YAG激光治疗，观察两组间的疗效及安全性。结果：在适合的脉宽及能量密度下，经过3～5次治疗，A组痊愈率74.4%，有效率86.0%；B组痊愈率90.7%，有效率100.0%，两组间痊愈率及有效率比较差异有统计学意义（P＜0.05）。总体不良反应发生率11.6%，主要表现为一过性红肿，两组间不良反应发生率无统计学差异。结论：强脉冲光联合长脉冲1064nm Nd：YAG激光治疗面部毛细血管扩张症疗效满意，不良反应轻，值得临床推广应用。“,”Objective To observe the clinical efifcacy and safety of intense pulsed light combined with long pulse l 064nm Nd:YAG laser in the treatment of facial telangiectasia. Methods 86 cases of facial telangiectasia were randomly divided into A and B groups, each group of 43 cases. Group A was treated by intense pulsed light alone, and group B was treated with intense pulsed light and long pulse l 064 nm Nd:YAG laser. The efifcacy and safety of the two groups were observed. Results In the appropriate pulse width and energy density, after 3 to 5 times the treatment,the cure rate of group A was 74.4%, the effective rate was 86.0%, the cure rate of group B was 90.7%and the effective rate was 100%. There were signiifcant differences between the two groups in the cure rate and the effective rate (P<0.05). The overall incidence of adverse reactions was 11.6%, mainly as a transient redness, the incidence of adverse reactions between the two groups were not statistically signiifcant. Conclusion The combination of intense pulsed light and long pulse l 064 nm Nd:YAG laser in the treatment of facial telangiectasia is satisfactory and has a mild side effect. It is worthy of clinical application.