下颌癌多系由颊粘膜、舌和牙龈的浸润。下颌转移癌主要原发于乳腺、甲状腺和肺。原发性下颌癌应与起自涎腺的骨内粘液表皮样癌相区别。牙源性囊肿恶变的报导不少,但原发性下颌癌的报导甚少。原发怀下颌癌由牙板鳞状上皮诱发较之牙胚剩余上皮诱发的可能性更大。Willis称此癌为原发性牙槽内上皮样癌。Pindborg和Praetorius则称之为原发性骨内癌。Shear将自己收集的此类病 Mandibular cancer is mostly infiltrated by buccal mucosa, tongue, and gums. Mandibular metastatic carcinoma is mainly found in the breast, thyroid and lungs. Primary mandibular cancer should be differentiated from the intraosseous mucoepidermoid carcinoma of the parotid gland. There are many reports of malignant transformation of odontogenic cysts, but reports of primary mandibular cancer are rare. The primary craniomandibular carcinoma is more likely to be induced by the squamous epithelium of the dental plate than the residual epithelium of the tooth germ. Willis called this cancer a primary alveolar epithelioid carcinoma. Pindborg and Praetorius are called primary intraosseous cancers. Shear will collect these diseases