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文献上记载有结核病患者应用对氨水杨酸时发生的并发症。但在我们所观察的一例患者中发现了特殊的、严重的并发症,并为时很长,现报告如下:患者P,男性,25岁,1955年10月8日因右侧浸润性肺结核溶解期而入院。入院时血液化验:血红蛋白13.3克,红血球406万,白血球10,100,嗜酸性2%,杆状核5%,中性69%,淋巴球18%,单核6%;血沉第一小时48毫米。从10月10日起,开始用链霉素(0.5克,每日一次)并用对氨水杨酸(每次10克)治疗。10月20日于右侧施行了人工气胸。治疗经过良好。体温转为正常,血沉减慢至第一小时225毫米。11月13日当患者使用了17克链霉素及340克对氨水杨酸之后,病情突然恶化:出现头痛,体温升高到38.8℃,并开始腹泻。次日发现面部皮膚
The literature documents the complications that occur in patients with tuberculosis when using salicylate. However, a specific and serious complication was found in one of the patients we observed, and was very long. The following is reported: Patient P, male, 25 years old, October 8, 1955 due to dissolution of right infiltrative pulmonary tuberculosis Period and admission. Admission blood test: hemoglobin 13.3 grams, red blood cells 4.06 million, 10,100 leukocytes, eosinophilic 2%, 5% of the nucleus, 69% neutral, lymphocytes 18%, mononuclear 6%; ESR 48 mm the first hour. Beginning on October 10, treatment with streptomycin (0.5 g once daily) and p-aminosalicylic acid (10 g each) started. On October 20, artificial pneumothorax was performed on the right. The treatment is good. Body temperature turned normal, ESR slowed to 225 mm in the first hour. On November 13, when the patient used 17 grams of streptomycin and 340 grams of p-aminosalicylic acid, her condition suddenly deteriorated: she developed headaches, raised her temperature to 38.8 ° C and started diarrhea. The next day found the facial skin