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天津市肿瘤医院自1979年首次成功地完成了第1例计划性不进行血管重建的肿瘤合并颈动脉分歧部切除术以来,到1993年共行此术20例。术后,除因其它原因死亡4例外,16例健在,始终未出现脑血管合并症。为了解颈动脉分歧部切除术后脑血流代偿供血机制,对术后健在的9例(第1组)及术前颈动脉压迫锻炼合格的6例(第2组)患者进行了彩色多普勒血流显像、经颅多普勒、氙脑图成像仪、颈脑血管数字减影造影、单光子计算机断层扫描及微机脑血流图等现代有关脑血流动力学及影像学的检测研究。多项检测研究结果显示:1)两组患者脑代偿供血均良好,表明切除一侧颈动脉后仍能充分代偿脑正常供血;2)脑血流代偿供血的主要方式是通过增加血流速度、增粗血管内径及开放脑底动脉环的交通支来完成;3)术前颈动脉压迫锻炼确实能起到促进脑侧支循环充分建立的作用,压迫锻炼须与脑血流图监测相结合,用以预测脑代偿供血状况
Tianjin Cancer Hospital successfully completed the first case of a planned revascularization-free tumor combined with a resection of the carotid arteries for the first time since 1979. Twenty cases had been performed in 1993. Postoperatively, except for 4 deaths due to other causes, 16 patients were still alive and cerebrovascular complications were not observed. In order to understand the mechanism of compensatory blood supply to cerebral blood flow after resection of the carotid artery, nine patients (group 1) after surgery and six patients (group 2) who had undergone preoperative compression of the carotid artery were color-coded. Pulrer flow imaging, transcranial Doppler, camphor-map imaging, digital subtraction angiography of the brain and cerebral vessels, single-photon computed tomography, and computer-based cerebral hemodynamics, and related modern cerebral hemodynamics and imaging Test study. The results of multiple tests showed that: 1) The cerebral blood supply of both groups was good, indicating that the normal blood supply to the brain can still be fully compensated after the removal of one side of the carotid artery; 2) The main way of blood flow compensation for cerebral blood flow is to increase the blood supply. Flow velocity, increased blood vessel inner diameter, and traffic branch opening of the cerebral aortic ring were completed; 3) Preoperative compression of the carotid arteries can indeed promote the establishment of a side branch circulation, and the compression exercise must be monitored with cerebral blood flow mapping. Combined to predict brain supply status