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先天弓形体病是由于孕妇急性感染弓形虫通过胎盘传播胎儿所致。早孕期感染可导致胎儿宫内死亡或严重的神经系统损伤。应用PCR技术对早孕绒毛、有不良妊娠史的中孕羊水和正常产妇血及新生儿脐血做弓形虫的检测,结果:100例早孕绒毛中有1例阳性,12例羊水中有2例阳性,其中一胎证实为无脑儿。100例产妇血中有2例阳性,100例新生儿脐血中有1例阳性。PCR方法在弓形虫虫血症期的血液低浓度弓形虫检测中显示有独到的优越性。用早孕绒毛行PCR产前诊断对开展优生工作有益。
Toxoplasmosis is due to the acute infection of pregnant women toxoplasma through the placenta caused by the fetus. Early pregnancy infections can lead to intrauterine fetal death or severe neurological damage. The PCR technique was used to detect Toxoplasma gondii in the first trimester of pregnancy, the second trimester of pregnancy with amniotic fluid and normal maternal blood, and neonatal umbilical cord blood. Results: 1 out of 100 cases of early pregnancy villus and 2 out of 12 cases of amniotic fluid were positive , One child confirmed no brain children. Two hundred cases of maternal blood were positive, one of 100 cases of neonatal umbilical cord blood was positive. The PCR method showed unique superiority in the detection of Toxoplasma gondii in the blood of toxoplasma gondii. Prenatal diagnosis of premature pregnancy using villus PCR beneficial for the development of eugenics.