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目的探讨部分脾动脉栓塞(PSE)术治疗肝炎后肝硬化,脾功能亢进的临床疗效及并发症。方法采用Seld inger方法,对56例肝炎后肝硬化、脾功能亢进者行部分脾动脉栓塞术,并注意栓塞面积,观察其脾脏缩小、血象变化及并发症的发生。结果56例中脾脏均有不同程度的缩小,最大可达8 cm;栓塞术后1周、4周复查血象中WBC、RBC、PLT均较栓塞前有明显升高(P<0.01);术后常见的并发症有疼痛、发热、胸水、腹胀、便秘等。结论部分脾动脉栓塞术治疗肝硬化并发脾功能亢进是一种安全程度高、疗效好的治疗方法。
Objective To investigate the clinical efficacy and complications of partial splenic arterial embolization (PSE) in the treatment of posthepatitic cirrhosis and hypersplenism. Methods Fifty-six patients with post-hepatitis cirrhosis and hypersplenism underwent partial splenic arterial chemoembolization using Seld inger method. The area of the embolization was observed. The spleen was reduced, the changes of blood and complication were observed. Results In all 56 cases, the spleen was reduced to a maximum of 8 cm. WBC, RBC and PLT were significantly increased at 1 week and 4 weeks after embolization compared with those before embolization (P <0.01) Common complications are pain, fever, pleural effusion, bloating, constipation and so on. Conclusion Some of the splenic artery embolization for the treatment of liver cirrhosis complicated with hypersplenism is a high degree of safety and efficacy of treatment.