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本文报导小儿骨髓增生异常综合征(MDS)5例。根据FAB 形态学分型;结合骨髓干细胞培养,染色体核型分析及骨髓活检确诊2例RA,2例RAEB及1例CMML。5例中1例死于颅内出血,4例在随访和治疗中。结合病例温习了有关MDS 诊断及小儿MDS 的文献。
This article reports pediatric myelodysplastic syndrome (MDS) in 5 cases. According to the morphological classification of FAB, two cases of RA, two cases of RAEB and one case of CMML were diagnosed in combination with bone marrow stem cell culture, chromosome karyotype analysis and bone marrow biopsy. One patient died of intracranial hemorrhage in 5 cases, and 4 patients were followed up and treated. Combined with the case review of the literature on MDS diagnosis and pediatric MDS.