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患者女性,46岁,因头晕、乏力一周于1998年3月26日入院。既往体健,重度贫血貌,双睑、口唇及甲苍白。实验室检查:血红蛋白53g/L,红细胞1.55×10~(12)/L,白细胞4.6×10~9/L,中性0.631,淋巴0.369。网织红细胞0.1％。血小极168×10~9/L。胸片示:右心缘片状致密阴影,胸部CT示:胸腺瘤可能性大。骨髓涂片示:骨髓增生活跃,粒系各阶段比值大致正常,形态未见异常,粒:红比值=23.4:1,红系各阶段增生明显低下,成熟红细胞未见异常,无网织红细胞,巨核细胞易见,血小板正常。诊断纯红细胞再生障碍性贫血。于1998年4月中旬在北京肿瘤医院手术,证实为胸腺瘤,术后病理诊断为良性胸腺瘤。
The female patient, 46 years old, was hospitalized on March 26, 1998 for dizziness and fatigue. Past health, severe anemia appearance, eyes, lips and a pale. Laboratory tests: hemoglobin 53 g/L, red blood cells 1.55×10 12/L, white blood cells 4.6×10 9/L, neutral 0.631, lymph 0.369. Reticulocyte 0.1%. Blood small pole 168×10~9/L. Chest radiographs showed densely shadowed right heart margins. Chest CT showed a high likelihood of thymoma. Bone marrow smear showed that the bone marrow hyperplasia was active, the ratio of the various stages of the granular system was approximately normal, and the morphology was not abnormal. The ratio of granules to red was 23.4:1. The hyperplasia of the erythroid stage was obviously low. No abnormalities of mature red blood cells and no reticulocytes were observed. Megakaryocytes are easy to see and platelets are normal. Diagnosis of pure red cell aplasia. The operation was performed at the Beijing Cancer Hospital in mid-April 1998 and confirmed as thymoma. The postoperative pathological diagnosis was benign thymoma.