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目的:探讨微型种植体支抗在青少年口腔正畸治疗中的作用及安全性、依从性。方法:选取宁波市医疗中心李惠利医院口腔科2017年3月至2019年3月收治的行口腔正畸治疗的青少年患者50例为研究对象，采用随机数字表法分为对照组和观察组，每组25例。对照组给予常规矫正治疗，观察组给予微型种植体支抗治疗。观察比较两组患者治疗有效率、上中切牙倾角差和牙齿凸距差、磨牙位移，以及安全性、不良反应和依从性的差异。结果:两组患者性别、年龄等差异均无统计学意义(均n P>0.05)。观察组上中切牙倾角差、牙齿凸距差和磨牙位移差距改善情况均明显优于对照组，差异均有统计学意义(n t＝11.328、20.011、17.336，均n P<0.05)；观察组口腔炎症、软组织水肿、矫正不适等不良反应发生率(8%)低于对照组(28%)，差异有统计学意义(χn 2＝10.225，n P<0.05)；观察组患者依从性(96%)明显高于对照组(80%)，差异有统计学意义(χn 2＝19.316，n P0.05). The improvement of the incisor angle difference, tooth crown distance difference and molar displacement difference in the observation group were significantly better than those in the control group, the differences were statistically significant(n t=11.328, 20.011, 17.336, all n P<0.05). The incidence of adverse reactions such as soft tissue edema, oral inflammation and discomfort of correction in the observation group (8%) was lower than that in the control group(28%), the difference was statistically significant(χn 2=10.225, n P<0.05). The compliance of patients in the observation group (96%) was significantly higher than that in the control group (80%), the difference was statistically significant(χn 2=19.316, n P<0.05).n Conclusion:The micro-implant anchorage is effective in the clinical treatment of adolescent orthodontics, with high safety and high patients’ compliance.It is worthy of clinical promotion.