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目的 进一步了解肾综合征出血热 (HFRS)患者血小板四项参数的动态变化和临床表现的关系 . 方法采用SysmexK - 10 0 0型自动血细胞计数仪对 47例HFRS患者血小板四项参数进行动态检测 .结果 HFRS患者在发热期、低血压休克期和少尿期血小板计数 (PLT)、平均血小板体积 (MPV)和血小板压积 (PCT)均明显降低 .临床上有多个部位出血表现的患者 ,其MPV和PCT比仅有皮肤粘膜出血点的患者显著降低 .至恢复期 ,上述三项指标均恢复到正常水平 .结论 动态监测HFRS患者血小板四项参数的变化对了解患者血小板功能状态及估计患者出血倾向的严重程度有一定的临床意义 .
Objective To further understand the relationship between the dynamic changes of platelet parameters and clinical manifestations in patients with hemorrhagic fever with renal syndrome (HFRS) .Methods Forty-seven patients with HFRS underwent dynamic detection of four parameters of platelet by using the SysmexK-100 automatic hemocytometer. Results HFRS patients had significantly lower platelet count (PLT), mean platelet volume (MPV) and platelet pressure (PCT) during the period of fever, hypotension and oliguria.Patients with multiple sites of clinical bleeding, MPV and PCT were significantly lower than those in patients with mucocutaneous bleeding alone.Under the recovery phase, the above three indexes returned to normal levels.Conclusion Dynamic monitoring of four parameters of platelet in patients with HFRSTo understand the functional status of patients with platelet and to estimate the patient’s bleeding The severity of the tendency has some clinical significance.