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胃癌居消化道恶性肿瘤首位,其发展是否受性激素调控已被关注。本文对89例胃癌组织作了雌激素受体(ER)检测,拟探讨ER表达的意义。 1 对象和方法胃癌89例,癌旁10例和胃溃疡11例。标本经石蜡切片HE和ABC-ER染色。结果作统计学处理。 2 结果 2.1 胃癌和非癌上皮ER阳性率及其定位溃疡旁及癌旁相对正常上皮的ER表达均阴性;胃癌ER阳性率33.7%(30/
Gastric cancer ranks first in the digestive tract malignancy. Whether its development is regulated by sex hormones has attracted attention. In this paper, 89 cases of gastric cancer were detected with estrogen receptor (ER), and the significance of ER expression was explored. 1 Subjects and Methods 89 cases of gastric cancer, 10 cases adjacent to cancer and 11 cases of gastric ulcer. Specimens were stained with paraffin sections HE and ABC-ER. The results were statistically processed. 2 Results 2.1 The positive rate of ER in gastric cancer and non-cancerous epithelium and its localization of ER near the paracancerous and para-cancerous normal epithelium were negative; the positive rate of ER in gastric cancer was 33.7% (30/