论文部分内容阅读
有实验报告认为,利福平能抑制体液和细胞免疫反应;能抑制人对结核菌素的迟发性过敏反应;以及在试管中当植物血凝素和结核菌素存在时,能抑制淋巴母细胞的转化。本文通过利福平对鼠异位心脏移植物存活时间的影响,以评价利福平可能存在的免疫抑制作用的机理。一组鼠行异位心脏移植后,静脉给予新配制的利福平,20mg/kg。结果表明心脏移植小鼠平均存活时间为9.4±0.7天,与对照
There are experimental reports that rifampicin can inhibit the humoral and cellular immune responses; can inhibit the person’s delayed allergic reaction to tuberculin; and in the test tube in the presence of phytohemagglutinin and tuberculin, can inhibit lymphoblastoid Transformation of cells. In this paper, the effect of rifampicin on the survival of rat heterotopic heart transplantation to evaluate the possible mechanism of rifampicin immunosuppression. After a series of murine heterotopic cardiac transplantation, the newly given rifampicin given intravenously, 20mg / kg. The results showed that the average survival time of heart-transplanted mice was 9.4 ± 0.7 days, compared with the control