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作者发现中药丹参(Salvia miltior rhiza的根)的提取物Ro09——0980,具有强烈的抗凝集活性,其抑制浓度(IC_(50))为6.6微克分子,为罂粟碱强度的20倍,与TILCOTIL相似。经紫外、红外、质谱、核磁共振四谱测定,Ro09——0680是一种新的菲酮类衍生物,分子式为C_(18)H_(16)O_2,熔点221——223℃,化学名为2异丙基——8甲基菲——3.4二酮。
The authors found that Ro09-9980, an extract of the Chinese medicine Salvia miltior rhiza, has a strong anti-agglutination activity with an inhibitory concentration (IC 50) of 6.6 μg, which is 20 times the strength of papaverine. TILCOTIL is similar. Through the UV, IR, MS and NMR tetra-spectrometry, Ro09—0680 is a new phenanthrene derivative with the molecular formula C 18 H 16 O 2 melting point 221-223°C. 2 Isopropyl - 8 methyl phenanthrene - 3.4 dione.