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CD4+T细胞表位通过激活CD4+T细胞从而介导并调节抗肿瘤或抗感染免疫反应。本文根据CD4+T细胞表位分析方法的最新研究进展,简要介绍CD4+T细胞表位预测分析法与实验鉴定法的基本原理和方法,为高通量筛选和鉴定CD4+T细胞表位提供指导。
CD4 + T cell epitopes mediate and regulate anti-tumor or anti-infective immune responses by activating CD4 + T cells. Based on the latest research progress of CD4 + T cell epitope analysis method, this paper briefly introduces the basic principles and methods of CD4 + T cell epitope prediction analysis and experimental identification method for high-throughput screening and identification of CD4 + T cell epitopes guide.