【摘 要】
：
目的探讨表没食子儿茶素没食子酸酯（EGCG）对慢性间歇性缺氧大鼠心肌的保护作用。方法将24只SD大鼠随机分为4组,每组6只。分为常压常氧组和慢性间歇性缺氧组（A组生理盐灌胃,B组50
【机 构】
：
湖南省儿童医院,桂林医学院附属医院
论文部分内容阅读
目的探讨表没食子儿茶素没食子酸酯（EGCG）对慢性间歇性缺氧大鼠心肌的保护作用。方法将24只SD大鼠随机分为4组,每组6只。分为常压常氧组和慢性间歇性缺氧组（A组生理盐灌胃,B组50 mg/kg EGCG灌胃,C组100 mg/kg EGCG灌胃）。分别在常压常氧和慢性间隙缺氧环境下饲养。8周处死动物,检测血清中过氧化物歧化酶（SOD）、谷胱甘肽过氧化酶（GSH-PX）活性及乳酸脱氢酶（LDH）含量。结果与慢性间歇性缺氧生理盐水组相比,EGCG组能明显抑制心脏的肥厚,并能升高SOD和GSH-PX的活性,降
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