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非甲非乙型肝炎是最常见的一种病毒性肝炎,占输血后肝炎的80%~90%。Rossetti等对18个月内未接受化疗的血液系统肿瘤患者进行了研究,以了解慢性乙肝表面抗原(HBsAg)阴性肝炎的流行情况,丙型肝炎病毒(HCV)标记的可信性及这组病人肝脏疾病的严重性。方法自1967至1990年,共557例。剔除化疗停止后血清转氨酶持续升高在1年以内的病人,因可能是化疗致肝脏毒性的结果。化疗停止后转氨酶持续升高12个月以上,HBsAg阴性者为慢性HBsAg阴性肝炎。每例病人1年1次用放射免疫法或酶免疫法测定HBsAg
Non-A non-B hepatitis is the most common form of viral hepatitis, accounting for 80% to 90% of post-transfusion hepatitis. Rossetti et al. Studied patients with hematologic malignancies who had not received chemotherapy within 18 months to understand the prevalence of hepatitis B virus (HBsAg) -negative hepatitis, the credibility of the hepatitis C virus (HCV) marker, and the group of patients Severity of liver disease. Methods From 1967 to 1990, a total of 557 cases. Excluding patients with persistent elevated serum aminotransferases in less than one year after chemotherapy is stopped may be the result of chemotherapy-induced liver toxicity. Aminotransferase continued to rise after 12 months of chemotherapy stop, HBsAg-negative chronic hepatitis B virus. HBsAg was measured by radioimmunoassay or enzyme immunoassay in 1 patient per patient