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清开灵具有清热解毒、化痰开窍和镇静安神等作用。现代药理研究表明其主要有解热[1]、抗炎免疫、保肝等作用。聚肌胞(POLY I:C)是TLR3的特异性配体,能诱导NF-κB和MAPK的活化。TLR3介导的信号途径中存在着MyD88非依赖途径[2,3]。细菌脂多糖(Lipopolysaccharide,LPS)是G-菌细胞
Qing Kai Ling with detoxification, phlegm resuscitation and sedative and other effects. Modern pharmacological studies have shown that it is mainly antipyretic [1], anti-inflammatory immune, liver and other effects. Polymyositis (POLY I: C) is a specific ligand for TLR3 that induces the activation of NF-κB and MAPK. MyD88-independent pathway exists in TLR3-mediated signaling pathway [2,3]. Bacterial lipopolysaccharide (LPS) is a G-cell strain