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A型肉毒毒素(BTA)被广泛应用于医学皮肤美容中.手术瘢痕和瘢痕疙瘩一直困扰患者,尽管对于瘢痕管理的早期干预备受关注,但目前临床上仍未有治疗方案共识.肉毒毒素注射在一些瘢痕的研究中已被证实安全、有效,也许未来会成为瘢痕重要的治疗手段.本综述将集中探讨瘢痕的形成和肉毒毒素作用于瘢痕的机制,以及讨论近年来相关的临床研究文献及其结果.“,”Botulinum toxin type A (BTA) is widely studied in the realm of aesthetic cutaneous medicine.Operational scars and keloid scar can be distressing.Despite elevated demand for an early intervention on surgery and keloid scars,there is still no universal consensus on optimal therapy plan.BTA injection has been proved safely and effectively in modulating surgery and keloid scars and may provide scar patient more promising treatment.This paper reviews literature on surgery and keloid scar formation,BTA therapeutic effect on scars mechanism and recent clinical study on scars treatment under research.