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目的探讨大剂量抗血小板聚集药治疗急性心梗患者静脉取血后局部按压时间与皮下出血的关系,寻找最佳按压时间。方法选取冠状动脉介入诊疗术术前拜阿司匹林300mg,氢氯吡格雷300mg,嚼服,术后应用替罗非班氯化钠注射液静脉滴注24 h左右,拜阿司匹林100 mgQD口服,氢氯吡格雷150mgQD嚼服,3 d以上患者150例,分为三组,第一组,第二组,第三组,按压时间分别为5 min,10 min,15 min,观察有无皮下出血及皮下出血的情况。结果通过比较发现,第一组与第二组第三组比较,差异有统计学意义(P<0.01)。结论冠状动脉介入诊疗术术前拜阿司匹林300mg,氢氯吡格雷300 mg,嚼服,术后应用替罗非班氯化钠注射液静脉滴注24 h左右,拜阿司匹林100 mg QD口服,氢氯吡格雷150 mg QD口服,3 d以上患者静脉取血按压10 min即能有效降低皮下出血发生,为最佳按压时间。
Objective To investigate the relationship between the local press time and subcutaneous hemorrhage after intravenous blood sampling in patients with acute myocardial infarction treated with high-dose anti-platelet aggregation drug in order to find out the best compression time. Methods Twenty-three hours after PCI, aspirin 300 mg and hydroch-clopidogrel 300 mg were chewed. Tirofiban sodium chloride injection was given intravenously for about 24 hours after operation. Aspirin was given orally 100 mg QD orally, Gray 150mgQD chewing clothes, 150 patients over 3 d were divided into three groups, the first group, the second group, the third group, the pressing time was 5 min, 10 min, 15 min, to observe the presence of subcutaneous hemorrhage and subcutaneous bleeding Case. Results By comparison, the first group and the second group of the third group, the difference was statistically significant (P <0.01). Conclusions Coronary interventional therapy before treatment of aspirin 300mg, hydrochloride clopidogrel 300 mg, chewing clothes, after intravenous infusion of tirofiban sodium injection about 24 h, aspirin 100 mg QD orally, hydrochlorothiazide Piraclitazone 150 mg QD orally, venous blood samples more than 3 d patients pressed 10 min that can effectively reduce the occurrence of subcutaneous hemorrhage, the best compression time.