论文部分内容阅读
目的探讨30例Barrett食管(Barrett esophagus,BE)的内镜下特点及与幽门螺杆菌(Helicobacter pylori,Hp)感染的关系。方法采用胃镜检查结合病理检查结果对30例BE患者进行分析,同时选取反流性食管炎及正常食管黏膜各50例作为对照组,采用快速尿素酶法及Warthin-Starry银染两种方法检测Hp感染。结果 30例BE中,以短段、舌型发病率最高,分别占83.33%和66.67%;组织学上,胃底型12例(40%),贲门型10例(33.33%),特殊肠化生型8例(26.67%)。食管部Hp的检出率,BE组阳性率明显高于反流性食管炎组和正常食管黏膜组(P<0.05)。胃窦部Hp的检出率,BE组显著低于反流性食管炎组和正常食管黏膜组(P<0.05)。结论本组BE病例内镜下以短段、舌型为主,Hp对BE可能有保护作用。
Objective To investigate the endoscopic features of Barrett esophagus (BE) in 30 patients and its relationship with Helicobacter pylori (Hp) infection. Methods Thirty patients with BE were analyzed by gastroscopy combined with pathological examination. Meanwhile, 50 patients with reflux esophagitis and normal esophagitis were selected as control group. Rapid urease and Warthin-Starry silver staining were used to detect Hp infection. Results Among 30 BE cases, the incidence rate of short segment and tongue type was the highest, accounting for 83.33% and 66.67% respectively. In histology, there were 12 cases (40%) of gastric fundus and 10 cases (33.33%) of cardia type. 8 cases of type (26.67%). The detection rate of Hp in esophagus and BE group was significantly higher than those in reflux esophagitis group and normal esophageal mucosa group (P <0.05). The detection rate of Hp in gastric antrum was significantly lower in BE group than in reflux esophagitis group and normal esophageal mucosa group (P <0.05). Conclusions This group of patients with BE cases endoscopic short segment, tongue-based, Hp may have a protective effect on BE.