Polymeric nanoparticles developed by vitamin E-modified aliphatic polycarbonate polymer to promote o

来源 :亚洲药物制剂科学(英文) | 被引量 : 0次 | 上传用户：go2mx

【摘要】

：

Oleanolic acid (OA) exhibited good pharmacological activities in the clinical treatment of hypoglycemia, immune regulation, acute jaundice and chronic toxic hep

【作者】

：

Wenjuan Zhang Chufan Liang Hao

【机构】

：

SchoolofPharmacy,HAISCO（Shenyang）PharmaceuticalCo.Ltd.,SchoolofPharmacy,SchoolofContinuingEducation,

【出处】

：

亚洲药物制剂科学(英文)

【发表日期】

：

2017年6期

【关键词】

：

Oleanolic acid POLYMERIC nanoparticles mPEG-PCC-VE ORAL delivery

【基金项目】

：

the National Natural Science Foundation of China,No.81373336,81473164.

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Oleanolic acid (OA) exhibited good pharmacological activities in the clinical treatment of hypoglycemia, immune regulation, acute jaundice and chronic toxic hepatitis. However, the oral delivery of OA is greatly limited by its inferior water solubility an

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Polymeric nanoparticles developed by vitamin E-modified aliphatic polycarbonate polymer to promote o

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