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目的了解艾滋病合并巨细胞病毒性视网膜炎的临床特征。设计回顾性病例系列。研究对象北京地坛医院眼科诊治的艾滋病合并新发巨细胞病毒性视网膜炎患者19例29眼。方法对所有19例患者29眼进行了与艾滋病相关的免疫学检测及肝肾功能检查;所有患者进行视力、眼压、裂隙灯、视野以及眼底照相等眼科检查,并观察其临床特征。主要指标视力,CD4+细胞,眼底改变。结果 19例患者中,10例双眼发病。中心型巨细胞病毒性视网膜炎5例6眼,其视力指数~0.4;周边型9例15眼,其中14眼视力>0.5;混合型5例8眼,其中7眼视力<0.6。17例CD4+细胞≤50个/μl。15例合并其他部位感染。结论巨细胞病毒性视网膜炎是艾滋病常见眼部并发症,周边型是其常见类型。CD4+细胞≤50个/μl的患者更易患病,其视力预后差。
Objective To understand the clinical features of AIDS complicated with cytomegalovirus retinitis. Design retrospective case series. Participants 19 cases (29 eyes) of AIDS patients with newly diagnosed cytomegalovirus retinitis were treated by ophthalmology department of Beijing Ditan Hospital. Methods All 19 patients had 29 cases of AIDS-related immunological tests and liver and kidney function tests; all patients with visual acuity, intraocular pressure, slit lamp, visual field and fundus photography and other eye examinations, and observe the clinical features. Main indicators of vision, CD4 + cells, fundus changes. Results Of the 19 patients, 10 had binocular disease. 5 cases of central cytomegalovirus retinitis in 6 eyes, the visual acuity index of 0.4; peripheral type in 9 cases 15 eyes, visual acuity of more than 0.5; mixed 5 cases 8 eyes, of which 7 eyes visual acuity <0.6.17 cases of CD4 + ≤50 cells / μl. 15 cases of other parts of the infection. Conclusion Cytomegalovirus retinitis is a common ocular complication of AIDS, peripheral type is its common type. Patients with CD4 + cells ≤ 50 / μl are more susceptible to the disease and have poor vision outcomes.