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目的:观察胃苏颗粒联合奥美拉唑、阿莫西林治疗慢性胃炎患者的临床效果以及对生存质量的影响。方法:纳入90例慢性胃炎患者,随机分为观察组以及对照组各45例。对照组给予奥美拉唑、阿莫西林治疗,观察组在对照组西药治疗的基础上口服胃苏颗粒治疗。2组均治疗4周。观察2组的临床疗效以及患者的生存质量。结果:观察组总有效率为93.33%,对照组总有效率为77.78%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组匹兹堡睡眠质量指数量表(PSQI)评分、日常生活自理能力表(ADL)评分与生活满意度指数(LSIA)比较,差异均无统计学意义(P>0.05);治疗后,2组各项分值均较治疗前改善(P<0.05),观察组改善的程度较对照组明显(P<0.05)。结论:胃苏颗粒联合奥美拉唑、阿莫西林治疗慢性胃炎患者可达到很好的治疗效果,并能同时提高患者的生存质量。
Objective: To observe the clinical effect of Weisu granule combined with omeprazole and amoxicillin in the treatment of patients with chronic gastritis and their effects on the quality of life. Methods: Ninety patients with chronic gastritis were enrolled and randomly divided into observation group and control group with 45 cases each. The control group was treated with omeprazole and amoxicillin, while the observation group was treated with Oral Weiweizu Granules on the basis of western medicine in the control group. Two groups were treated for 4 weeks. The clinical efficacy and quality of life of the two groups were observed. Results: The total effective rate was 93.33% in the observation group and 77.78% in the control group. There was significant difference between the two groups (P <0.05). Before treatment, there were no significant differences between the two groups in PSQI score, ADL score and life satisfaction index (LSIA) (P> 0.05). After treatment, The scores of 2 groups improved compared with that before treatment (P <0.05), and the degree of improvement in the observation group was significantly higher than that of the control group (P <0.05). Conclusion: Weisu granule combined with omeprazole, amoxicillin in patients with chronic gastritis can achieve good therapeutic effect, and can improve the quality of life of patients.