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通过小肠原位闭式灌流方法探讨了某些营养元素及维生素对大鼠小肠铅吸收的影响。体重280g左右Wistar大鼠分两组（各6只），对照组灌流液成分：40mgPb2/L蒸馏水；实验组灌流液成分：40mgPb2＋5g氯化钙＋1g醋酸锌＋5g氯化铁＋2mg亚硒酸钠＋30mgVitaminB1＋35mgVitaminB6＋10mg叶酸／L蒸馏水。灌流小肠长度15cm左右，灌流液20mL，时间20min，流速2mL/min。结果显示，实验组门静脉血铅浓度明显低于对照组（P＜0．01），说明本实验中所涉及各营养素联合应用能减少铅在大鼠小肠的吸收，但各自作用的贡献尚需进一步研究。
The effects of some nutritional elements and vitamins on intestinal absorption of lead in small intestine were investigated by the method of closed intestinal perfusion in situ. Body weight 280g Wistar rats were divided into two groups (6 each), the control group perfusion fluid composition: 40mgPb2 / L distilled water; experimental group perfusate: 40mgPb2 +5 g calcium chloride +1 g zinc acetate +5 g ferric chloride +2 mg sodium selenite +30 mgVitaminB1 +35 mgVitaminB6 +10 mg folic acid / L distilled water. Perfusion intestinal length of about 15cm, perfusion fluid 20mL, time 20min, flow rate 2mL / min. The results showed that the experimental group of portal blood lead levels were significantly lower than the control group (P <0.01), indicating that the experiments involved in the combination of nutrients can reduce the absorption of lead in the small intestine of rats, but their contribution to the role needs further the study.