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目的探讨强脉冲光(intense pulse light,IPL)对中厚皮片供区瘢痕预防性治疗的疗效。方法将38例自体大张中厚皮片移植术的烧伤或整形患者被分为两组:IPL治疗组21例,对照组例17例。皮片供区自然上皮化愈合后,治疗组采用IPL对中厚皮片供区瘢痕进行预防性治疗,每次间隔3～4周,治疗4～5次,并以弹力衣或弹力套压迫,外贴瘢痕敌胶片等行辅助性抗瘢痕治疗;对照组只辅助性进行抗瘢痕治疗,不做IPL治疗。治疗后以温哥华瘢痕量表对供皮区瘢痕进行评分,评估疗效。结果随访12个月,IPL治疗组中厚皮片供区增生瘢痕逐渐变平滑,色素沉着逐渐消退;对照组出现明显瘢痕增生和色素沉着。两组温哥华瘢痕量表评分比较差异有显著意义(P<0.05)。结论 IPL是一种有效的防治中厚皮片供区瘢痕增生和色素沉着的治疗方法,操作简单,不良反应少。
Objective To investigate the curative effect of intense pulse light (IPL) on the preventive treatment of scar in middle-thick skin graft. Methods Thirty-eight patients with burn or plastic surgery under autologous large and medium-thickness skin grafts were divided into two groups: 21 in the IPL group and 17 in the control group. The skin graft for natural epithelialization after healing, the treatment group using IPL for the prevention of scar for the middle and thick skin graft area, each interval of 3 to 4 weeks, the treatment of 4 to 5 times, and compression vest or elastic sleeve, Outside the scars of enemy films and other auxiliary anti-scar treatment; control group only assisted anti-scar treatment, not IPL treatment. After treatment with scars on the Vancouver scar for donor area scoring, evaluation of efficacy. Results At the 12-month follow-up, hypertrophic scars gradually became smooth and the hyperpigmentation of the hyperplastic scar in the IPL treatment group gradually subsided. In the control group, obvious scar hyperplasia and hyperpigmentation were observed. There was significant difference between the two groups in Vancouver scar scale (P <0.05). Conclusion IPL is an effective method for the treatment of scar hyperplasia and hyperpigmentation in middle and thick skin slices, with simple operation and few adverse reactions.